Milbemycin is a new type of semi-synthetic macrolide anthelmintic. It is an oxime derivative of Milbemycin A3 and A4. The molecular weight of A3 oxime is 541.7, and the molecular weight of A4 oxime is 555.7. In terms of application, milbexime can be used alone or in combination with nitenpyram, lufenuron, spinosad, praziquantel, etc. to form a compound preparation, which can effectively prevent and control heartworms, hookworms, roundworms, whipworms, roundworms and other internal parasites, as well as hair follicles, scabies, lice, fleas and other external parasites. Milbexime acts as an agonist of the GABA (gamma-aminobutyric acid) neurotransmitter in nerve cells and also binds to glutamate-gated Cl
